Abnormal Psychology
Diabetes Mellitus (DM) is often accompanied by other complications, such as symmetric distal polyneuropathy (SPDN), which is a progressive neural impairment that affects the central nervous system and peripheral nerves. This disorder is characterized by pain, especially in the foot, that is characteristically exacerbated at night. Individuals with DM may also be more prone to the development of psychiatric disorders, particularly mood disorders. What is not known, however, is if patients with DM that also present with SPDN exhibit mood disorders at an increased rate in comparison to DM patients without SPDN. The objective of the study conducted by Moreira, Papelbaum, Fontanelle. Appolinario, Ellinger, Coutinho, and Zagury (2007) was to determine the frequency of psychiatric comorbidity in DM patients with SPDN in comparison to DM patients without SPDN. The relationship between symptoms of depression and symptoms/signs of SPDN were also investigated by the researchers. The hypothesis of this study was that there would be a significant association between the presence of SPDN among patients with DM and the pre
However, it is not clear whether SPDN or the presence of psychiatric disorder could be considered chronologically primary. Finally, blood glucose levels were measured through venous blood samples from all DM patients that were collected after a 12-hour fast. Also, the severity of depressive symptoms was found to be positively correlated with the severity of SPDN symptoms (r=0. Results The presence of SPDN was identified in 22 participants, which constituted 33. Protocol for the study was approved by an ethics committee and written and informed consent was obtained from all participants after they received information regarding procedures that were involved in the study. Two-tailed t-tests were used to analyze continuous variables and Fisher's exact test was used to study categorical data in the comparison of DM patients with SPDN to DM patients without SPDN. The mean score of these two measures was used as the final score. Based on these criteria, three participants were excluded. The Structured Clinical Interview for DSM-IV/Patient version (SCID-I/P - Axis I Disorder) was used to assess the prevalence of psychiatric disorders among the DM patients. Furthermore, a trend toward worse glycemic control was identified among DM patients with SPDN in comparison to DM patients without SPDN (P=0. These measures cover both signs and symptoms of SDPN. The most significant findings of the study were that individuals with DM and SPDN exhibited axis I psychiatric disorders significantly more than DM patients without SPDN, and that there was a positive correlation between the severity of depressive symptoms and the severity of SPDN symptoms.
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