Genetic Screening for Factor V Leiden
Is generalised Genetic Screening for Factor V Leiden Necessary?Genetic screening has no doubt have been the one of the most controversial issue in the branch of medicine.The new issue has recently triggered the on-going debate: the dilemma of whether the Government should allow the Genetic screening of all 16 year old girls for mutation in specific gene called the Factor V which sometimes lead to condition called the DVT , or not.In the essay I will suggest on why we should not do the screening.In the first paragraph of my essay I shall briefly explain the science behind the Factor V Leiden including the cause, inheritance, test and interpretation of the result..In my second I shall defend my argument considering the ethical, social and also economical side on the Genetic screening.Lastly the conclusion will consist of dealing with all the pros and cons of the technology and weighing up the advantage and disadvantage and my final conclusion will be made.Factor V itself is a clotting factor, whose role is to help blood to clot when an appropriate trigger is present. However, like all steps in the complex clotting cascade, Factor V is subject to regulation to keep it under control so that clots don't form
There are some of benefit proven screenings such as breast cancer screening or hip replacements for the elderly, which will provide benefit for the individual society and the majority. Different conditions can be inherited in different ways. If this is the case, does it worth testing on all of the country's high school female students spending millions of dollars, just to grab 3% of those who only have 8 in 1000 chance of getting DVT which is not a deadly disease and also when it is still uncertain whether the testing will be beneficial or not?Not only economically but also socially and ethically the testing is wrong. This is called dominant inheritance. The accuracy of the test is almost 100 %. There is nothing an individual can do to alter this chance. If one of them was homozygous for the gene mutation, their child will definitely inherit it. Because of all the danger of Factor V Leiden, test is necessary especially for those who already suffered venous thrombosis, has a family history of the disease etc. It is involved in 20-40% of cases and is present in 3% of the general population. Can Factor V Leiden be inherited?Genetic mutations are passed from generation to generation. Risk is increased still further in situations such as pregnancy, oral contraceptive use, estrogen therapy, malignancy, diabetes mellitus, immobilization, surgery, trauma, high blood pressure, obesity, smoking or long time travel (commonly called economy class syndrome). If a person is homozygous, (both mutated gene) they are at a greater risk to develop a blood clot than an individual who is heterozygous. 2% of the general population was found to be heterozygous. When mutated it is not destroyed by Protein C or S causing a unnecessary clot in our body.
Common topics in this essay:
Factor Leiden,
DVT PE,
Leiden Genetic,
Leiden Potential,
factor leiden,
Normally APC,
Leiden Factor,
Guanine Adenine,
venous thrombosis,
gene mutation,
genetic screening,
blood clot,
clotting factor,
Protein APC,
develop blood clot,
normal copy,
deterioration mental,
factor mutation,
risk develop,
risk develop blood,
,
normal copy gene,
factor leiden mutation,
1000 chance thrombophilia,
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Acceptance Essays
