disease
The Mysteries Surrounding Creutzfeldt-Jakob Disease Creutzfeldt-Jakob Disease is a killer. What we know is that it wastes no time. Creutzfeldt-Jakob Disease will kill a person within one year of contraction. It is yet unknown how Creutzfeldt-Jakob Disease chooses its victims, but it does seem to have accomplices, known as the spongiform encephalopathies, in the rest of the animal kingdom. It is possible that it may be known what means Creutzfeldt-Jakob Disease uses in order to annihilate its victims, but the theory surrounding that is still controversial. By examining the facts and observing the evidence we shall one day uncover the truth behind this malicious killer. Creutzfeldt-Jakob Disease is a rare neuro-degenerative disease. Creutzfeldt-Jakob Disease is a rare neuro-degenerative disease that leads to the loss of coordination, dementia and death. Death usually occurs within a year of the onset of symptoms. Creutzfeldt-Jakob Disease is a human disease and can be dormant for as long as thirty years. The average age of onset is sixty years, but there are recorded instances of onset as easily as sixteen years and as old as 80 years. It is estimated that, world-wide, between 0.5 and 1 case per million population
In addition, the clinical course of the disease was atypical of classic Creutzfeldt-Jakob Disease. Kuru is the condition that first brought prion diseases to prominence in the 1950's. The officially reported rate of Creutzfeldt-Jakob Disease incidence is less than one case per million people per year (World). In younger victims the disease could look like multiple sclerosis or a severe viral infection, according to Alzheimer's expert Gareth Roberts (Brain). Also known to affect humans are GSS (Gertmann-Straussler-Scheinker syndrome), FFI (Fatal Familial Insomnia), Kuru, and Alpers Syndrome. This explains why some cases of Creutzfeldt-Jakob Disease in humans appear to be inherited. At Yale, out of 46 patients clinically diagnosed with Alzheimer's, 6 were proven to have actually had Creutzfeldt-Jakob Disease at autopsy (Manuelidis). Increased incidence in some regions of the world has been attributed to the possibility of a genetic predisposition. Eventually death occurs and the brains of these animals strongly resemble sponges. Twenty percent or more of people clinically diagnosed with Alzheimer's disease are found at autopsy to not have had Alzheimer's at all (McKhann). Scrapie was the first example of spongiform encephalopathy to be noticed and has been known about for many hundreds of years. In addition, if new variant Creutzfeldt-Jakob Disease is associated with Bovine spongiform encephalopathy, there is the possibility that cattle-to-human transmission of disease has occurred in other countries where Bovine spongiform encephalopathy exists (CDC). The pathogeneses of FFI are largely unknown. However, on March 20, 1996 the Spongiform Encephalopathy Advisory Committee (SEAC) of Great Britain announced that 10 cases of a previously unrecognized form of Creutzfeldt-Jakob Disease had been identified and may be linked to the Bovine spongiform encephalopathy epizootic in Great Britain, where more than 155,000 cattle were affected from 1986 through 1995.
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