Subjects:
learn that they have a disease called leukemia.
Leukemia is a type of cancer. Cancer is a group of more than 100 diseases that have two important characteristics in common. One of those is that certain cells in the body become abnormal. The other characteristic is that the body keeps producing large numbers of these abnormal cells.
Leukemia is cancer of the blood cells. To understand leukemia, it is helpful to know about normal blood cells and what happens to them when leukemia develops.
The blood is made up of fluid called plasma and three types of cells. Each type has special functions.
White blood cells - help the body fight infections and other diseases.
Red blood cells - carry oxygen from the lungs to the body's tissues and take carbon dioxide from the tissues back to the lungs. The red blood cells give blood its color.
Platelets - help form blood clots that control bleeding.
Normally, blood cells are produced in an orderly, controlled way, as the body needs them. This process helps keep us healthy. When leukemia develops, the body produces large numbers of abnormal blood cells. In most types of leukemia, the abnormal cells are white b
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The following are the most common types of leukemia:
Acute lymphocytic leukemia (ALL) is the most common type of leukemia in young children. In chronic leukemia, some blast cells are present, but in general, these cells are more mature and can carry out some of their normal functions. The computer has given us the Internet. Conventional chemotherapy is unable to modify the natural history of the disease. It is certain that interventions specific for control of the malignant transformation will be identified. Higher doses of infused stem cells translate into lower relapse rates.
The problems encountered and the strategies that have been used to improve the outlook in older adults with AML are the following.
CLL results from an acquired (not inherited) injury to the DNA of a single cell in the bone marrow. The two main strategies for improving outcomes in older adults with AML are to develop effective chemotherapeutic regimens with improved tolerability, and to reduce drug resistance. There is no prospective randomized study testing the two approaches in the good--standard-risk population. reduced tolerance to chemotherapy and comorbidity).
AMLs of older subjects display several biological overlaps with secondary AMLs including multilineage involvement, phenotype, unfavorable cytogenetics and elevated activity of multidrug resistance genes. The signal transduction inhibitors, small molecules bioavailable orally and specific for interfering with signals resulting from ligand-receptor interactions, are a dramatic advance. In only 35-40 years not only have techniques for the early detection, prevention, and surgical and radiation therapy treatments improved, but at least 15-20% of patients with systemic/metastatic cancers can be cured with our current primitive systemic treatments.
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