Malaria Genome Project
“The Malaria genome project, brings new hope” Malaria is one of the world’s most serious infectious diseases. According to the World Health Organization, it kills 2.5 million people and infects 500 million each year worldwide. Malaria occurs in 100 countries, placing 40% of the world’s population at risk. About 90% of cases are in tropical regions of Africa. About 95% of deaths are Africans under the age 5. The most common form of malaria is the product of a nefarious partnership between the Anopheles Gambia mosquito and the Plasmodium Falciparum parasite. Mosquitoes pick up the parasite by feeding on an infected human host. The parasite lives in the mosquito’s gut until the mosquito bites another human. Malaria is currently reoccurring in many countries where it had been under control for decades. Anti-malarial drugs have lost much of their effectiveness. Plasmodium has evolved resistance to several drugs in many areas, . . .
The teams then used computers to sort through the information from the segments and put the genetic Humpty Dumpy back together again in a virtual form. Research An international team of scientists from the “Malaria Genome Project” has achieved a breakthrough that is expected to lead to the prevention and treatment of one of the world’s most serious infectious disease. A genome is the genetic instruction manual for any organism. Pesticides used to control Plasmodium’s vector, the mosquito, are also losing their effectiveness. Scientists sequenced the genomes by separating the organism’s chromosomes, long chains of DNA organized into genes. It might eventually lead to a vaccine. Although, this project has shown some success in lab, the actual release of such mosquitoes into the wild poses all sorts of questions and ecological hazards. The reassembled sequences were then checked for accuracy, yielding a final draft of the parasite genome that is 98 percent complete. These scientists report they have sequenced the genomes of both the parasite responsible for infections in humans and of the mosquito that carries the parasite. therefore, necessitating the use of a combination of drugs. So, new targets for development of anti-malaria drugs have emerged. In addition to this, researchers say that they have uncovered the gene that, through mutation, has given the parasite resistance to one of the leading anti-malaria drugs. This work was done by cheaper, more efficient, and faster machines. But right now, scientists say that they are still a long way from zapping the mosquito scourge.
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