urther to see if it is resistant to any of the drugs commonly used to treat tuberculosis. If someone has a positive PPD but does not have any signs or symptoms of active disease, he or she is said to have Latent TB infection. It is generally recommended that people with Latent TB infection begin taking drug therapy to prevent the infection from developing further. If someone has a positive PPD and has signs and symptoms of tuberculosis, he or she is said to have Active TB. Treatment is necessary for someone with active TB, which usually involves a combination of antibiotics to treat the infection.
PPD testing in people with HIV can be challenging. PPD testing doesn't test for the presence of Mycobacterium tuberculosis, but instead looks for signs that the immune system is currently fighting the bacteria. In HIV infected patients with compromised
immune systems, there might not be enough immune activity to either fight the infection or respond to the PPD test. In other words, the bacteria might be present
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