the presynaptic neuron, releases a neurotransmitter into the space between the neuron and a neighboring cell. The neurotransmitter then attaches to a neighboring cell to trigger a specific activity. Antidepressants work by interacting with neurotransmitters at three different points: they can change the rate at which the neurotransmitters are either created or broken down by the body; they can block the process in which a spent neurotransmitter is recycled by a presynaptic neuron and used again; or they can interfere with the binding of a neurotransmitter to neighboring cells.
All antidepressants decrease symptoms of depression in about 70 percent of depressed people who take them. These medications appear to work by altering the levels of serotonin, norepinephrine, and other neurotransmitters in the brain. Most antidepressants take about two to three weeks of treatment before they began to work. Research has shown that no antidepressant is more effective than the others are, doctor
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