s have shown statistical associations between enamel hypoplasias and a variety of clinical conditions of which we will only mention a few here: premature birth, malnutrition, fluorosis, high fever, localized trauma and systemic metabolic distress such as gastrointestinal disorders.
             Dental plaque is a mixed microbial biofilm growing on teeth and is the prime aetiological agent of the two main oral diseases, dental caries and periodontal disease. The microbial composition of plaque varies between individuals and the location on the tooth and generally reflects the complex nature of the ecology of the mouth.
             In common with other biofilms, the microbial composition of dental plaque is capable of change in response to changes in the environment, notably the diet. These responses are modulated by homeostatic mechanisms inherent in the plaque in ways, which are as yet poorly understood.
             The major sites of plaque accumulation are in the fissures of molar teeth, in the area bounded by marg
             ...