in the liver, pancreas, and kidneys.
             Creatine monohydrate is an essential part of the primary energy source used for muscle contraction. It exists in two different forms, one as a free (chemically unbound) Creatine and the other a Creatine phosphate, which makes up 2/3's of the body's total Creatine supply. When your muscles contract, the initial fuel for this movement is a compound called ATP (andenosine triphosphat). As the muscles keep contracting the ATP release one of it's molecules, thus becoming a different compound called ADP. ATP provides energy for about ten seconds, so for muscle contraction to continue, more ATP must be produced. ADP causes your muscles to fatigue. Creatine phosphate comes to the rescue by giving up its phosphate molecule to ADP, recreating ATP. This ATP can then be burned again as fuel for more muscle contraction. The primary purpose of phosphocreatine is to re-supply ADP with high-energy phosphates to buffer levels of ATP when ATP levels are falling rapidly as in intense exercise. ATP is the only direct source of energy that can be used by the cells. Glucose and free fatty acids are metabolized to eventually produce ATP, which the cell utilizes to do work such as muscular contraction. Skeletal muscle fatigues if ATP levels fall below 25-30% (ATP levels can not fall below 70%)(3). Creatine phosphate then acts as a reserve of high-energy phosphates. It transfers its phosphates to ADP to regenerate ATP while the glycolytic pathway is still "warming-up". Indeed it has been shown in studies that phosphocreatine usage peaks within a third of the time it takes for glycolysis to peak (which takes three seconds)(2). There is also a 3-to-1 ratio of phosphocreatine to ATP this allows ATP to be regenerated from ADP at a faster rate than the ATP is depleted (3).
             The bottom line is that your ability to regenerate ATP depends on your supply of Creatine. The more Creatine monohydrate availab...