n clinical studies. Some athletes use 10 to 100 times the amount their bodies produce.
Anabolic steroids are primarily the result of research to develop drugs that would separate the tissue-building capability of testosterone from its masculinizing properties. This separation has never been accomplished. By 1935, the basic nature of its anabolic and androgenic effects had been recognized by Dr. Charles Kochakian, who most experts consider the "Father of Steroids." He showed that a hormone-like extract from male urine stimulated a strong positive nitrogen balance in castrated dogs. A positive nitrogen balance indicated the synthesis of new tissue proteins in dogs and humans. The anabolic properties of testosterone were established. Further research in rats showed the positive nitrogen balance was also associated with non-fat body weight.
Through the 1940s, scientists attempted to achieve the tissue-building effects without the masculinizing effects of testosterone. Dr. Kochakian, concerned with the possible misuse of anabolic steroids, wrote, "All of the modified steroids still remain sufficient virilizing (masculinizing) activity to make them objectionable as therapeutic, especially in children and women." (Yesalis 34) The use of anabolic steroids wasn't introduced to the sporting arena until the 1940s and 1950s. The Russian weight lifting team won several medals in the 1952 Olympics, partly due to synthetic testosterone use. An American physician determined that US competitors should have the same advantage.
By 1958, physicians realized the drug had surfaced widely
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