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complications that result from this cancer and others are the clogging and
cramming of the system (American Cancer Society, 1999: 10)
have been named as a great cause of cancer. It now is thought in the medical
community that while there are definite environmental contributors to cancer,
even those people who are exposed to few carcinogens may suffer from disease
that runs in their families. Among the genes that are being heavily researched
is the gene BRCA1 (Case Studies). In one of the preliminary studies of this
particular gene, over 250 Jewish women were discovered to have mutations in
this germ-line allele, which is a version of the trait that is passed to the
offspring through the germ line cell (or gamete). This accounts for
approximately 13% of all breast cancer patients observed. Jewish women in
specific were used, as early on there was a definite pattern of breast cancer
through the Jewish community especially that which lived in the United States.
The specific mutation, 185delAG, was, "strongly associated with the onset of
breast cancer in Jewish women before the age of 30." Scientists advanced upon
this new information of genealogical interplay, so the "New England Journal of
Medicine" (NEJM) set out determined to study the overall effects of these
genes. In an article printed on January 18, 1996, germ-line alterations in
BRCA1 were discovered in six of the 80 women surveyed who had breast cancer
but had no apparent familial history of it. Thus the scientists concluded that
mutation was not limited to women with a history of cancer. Genes are thought
to cause five to twenty percent of all breast cancers. A gene known as p53
supposedly stalls reproduction of cells, and can even cause a cell to "commit
suicide". Other genes that seem to accelerate growth to overtake and stick to
proteins include HER2, neu, and erB2 (Fitzgerald et al, 1996). The relation
between serum estro...